基于作战环的不同节点攻击策略下的作战网络效能评估

基于作战环思想, 以作战网络抽象模型为基础, 围绕作战环的分类、定义、形式化描述、数学模型等基本问题开展了理论研究, 进一步丰富了作战环理论体系。同时, 以能否快速有效打击对方目标实体为根本依据, 建立了基于目标节点打击率和基于目标节点打击效率的作战网络效能评估指标。通过仿真实验, 将作战环相关理论运用于不同节点攻击策略下的作战网络效能评估, 为实际作战体系对抗中双方的攻击与防护提供应用指导, 也为进一步开展基于作战环的作战网络应用研究提供参考借鉴。     

基于改进Lagrange乘子法的交通信号配时优化研究

为提高交叉口的机动车通行效率及环境效益,采用改进罚参数来构造一种新的Lagrange乘子法对交叉路口的交通信号进行优化配时。通过权重系数建立车辆延误与尾气排放的数学模型,利用改进Lagrange乘子法进行优化,将其结果与两种典型智能算法的优化结果进行对比,并利用VISSIM(Verkehr in Stadten Simulation)微观交通可视化仿真软件进行验证。实验结果表明,该方法优化的信号配时使车辆延误降低19.89%,尾气排放量降低2.379%,可见大比例优化了交叉口的车辆延误,同时可以降低尾气排放量。     

基于回波预处理和相参积累的C&I干扰抑制算法

C&I(chopping and interleaving)干扰是一种针对线性调频(linear frequency modulation, LFM)雷达的典型干扰样式, 干扰子信号调频斜率与雷达发射信号相同, 利用信号处理工具分离真实回波与干扰信号难度较大。针对该问题, 以LFM相参雷达抗自卫式C&I干扰为背景, 提出基于回波预处理和相参积累的干扰抑制算法。根据估计的回波时延, 设置距离窗截取受干扰回波段, 在此基础上, 通过对回波预处理, 改变不同重复周期内假目标的快时间位置分布, 通过相参积累实现干扰抑制。仿真试验表明, 所提算法能够有效抑制强干扰背景下的C&I干扰, 干扰抑制后真实目标检测概率大幅提高, 虚假目标数量明显减少。     

基于不平衡数据的公司破产预测研究

整合创新数据预处理技术与集成算法利用不平衡数据探讨了公司破产预测问题。首先，运用冗余信息处理方法、不同抽样方法等对不平衡数据进行预处理。其次，以5.0分类器（Classifier 5.0,C5.0）决策树和单隐层前馈神经网络作为基分类器，分别与三类重抽样数据预处理技术结合，择出最优抽样法。再次，结合自助汇聚法提升分类效果，并运用十折交叉验证的受试者操作特征曲线的下方面积进行评价，对比了两基分类器的集成模型。最后，运用加利福尼亚大学尔湾分校数据库中一万多家波兰制造业公司的实际数据进行实验验证。实验结果表明：欠抽样或人工少数类过采样法与神经网络结合的集成模型分类效果最优，为企业实施破产预测提供积极支撑。     

联合卫星定位和测量机器人的超高层建造过程水平位移监测

在超高层建筑建造过程中,常用测量机器人监测中间楼层的监测点的变形。削弱建筑晃动影响对于监测结果的稳定性至关重要。为此,首先提出一种利用楼顶卫星接收机测量建筑晃动情况,通过内插得到中间楼层瞬时晃动影响的方法,并通过实验验证该方法的有效性。在此基础上,利用该方法对多期监测数据进行处理,结果表明该方法可获得更加稳定的监测结果。将处理结果与有限元分析的结果进行比较,结果表明使用该方法后监测结果与有限元分析的结果吻合度较高。     

基于LabVIEW与SQL server设计的浮标电源远程管理系统

针对现有海洋浮标缺乏对电源有效监控管理的问题，提出了一种基于LabVIEW与SQL server编程，结合C8051F021单片机硬件的方法，设计了岸站服务器的终端监控软件和安装于浮标上的硬件电路。通过网络或北斗通讯等实时通讯方式，实现对浮标上电源的实时监控和管理，提高了浮标电源的利用和管理的能力。     

Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses in head and neck squamous cell carcinoma

The NLRP3 inflammasome is a critical innate immune pathway responsible for producing active interleukin (IL)-1β, which is associated with tumor development and immunity. However, the mechanisms regulating the inflammatory microenvironment, tumorigenesis and tumor immunity are unclear. Herein, we show that the NLRP3 inflammasome was over-expressed in human HNSCC tissues and that the IL-1β concentration was increased in the peripheral blood of HNSCC patients. Additionally, elevated NLRP3 inflammasome levels were detected in tumor tissues of Tgfbr1/Pten 2cKO HNSCC mice, and elevated IL-1β levels were detected in the peripheral blood serum, spleen, draining lymph nodes and tumor tissues. Blocking NLRP3 inflammasome activation using MCC950 remarkably reduced IL-1β production in an HNSCC mouse model and reduced the numbers of myeloid-derived suppressor cells (MDSCs), regulatory T cells (Tregs) and tumor-associated macrophages (TAMs). Moreover, inhibiting NLRP3 inflammasome activation increased the numbers of CD4⁺ and CD8⁺ T cells in HNSCC mice. Notably, the numbers of exhausted PD-1⁺ and Tim3⁺ T cells were significantly reduced. A human HNSCC tissue microarray showed that NLRP3 inflammasome expression was correlated with the expression of CD8 and CD4, the Treg marker Foxp3, the MDSC markers CD11b and CD33, and the TAM markers CD68 and CD163, PD-1 and Tim3. Overall, our results demonstrate that the NLRP3 inflammasome/IL-1β pathway promotes tumorigenesis in HNSCC and inactivation of this pathway delays tumor growth, accompanied by decreased immunosuppressive cell accumulation and an increased number of effector T cells. Thus, inhibition of the tumor microenvironment through the NLRP3 inflammasome/IL-1β pathway may provide a novel approach for HNSCC therapy.     

磁流变液中磁性颗粒成链与团聚的临界特征分析

热运动对纳米级磁流变液系统的颗粒团聚行为和宏观流变特性扰动影响不可忽视.为研究施加外磁场后系统微结构与热运动间的关系，探讨在不同颗粒粒径情况下热运动能量在系统总能量中的占比.采用CCD设计方法，分析Monte Carlo仿真获取的颗粒位形信息，生成关于外磁场磁感应强度、颗粒粒径和体积分数的系统热耦合系数<λ>回归模型;成链团聚的临界颗粒粒径计算值比文献经验值高出约23%，证实在考虑系统内多因素的综合影响下，纳米级磁流变液具有更严格的流变现象临界发生条件.     

Loewy矩阵与几乎Koszul代数

几乎Koszul代数作为Koszul代数的推广,在代数周期性和分次自入射代数的研究中起到了重要的作用.几乎Koszul代数的刻画是一个复杂的计算问题,而Loewy矩阵为Koszul代数的刻画带来了较为直观的计算方法.通过经典的Loewy矩阵和构造增广Loewy矩阵,利用分次代数分次模的两种不同Loewy维数向量得到了一个分次模成为d-线性模的充分必要条件,并得到了一个有限维分次代数成为几乎Koszul代数的充分必要条件,从而推广郭晋云利用Loewy矩阵刻画Koszul代数的相关结果.     

粉末冶金法制备混杂增强铜基复合材料的增强体竞争析出行为研究

Copper matrix composites reinforced by in situ-formed hybrid titanium boride whiskers (TiB_w) and titanium diboride particles (TiB_2p) were fabricated by powder metallurgy. Microstructural observations showed competitive precipitation behavior between TiB_w and TiB_2p, where the relative contents of the two reinforcements varied with sintering temperature. Based on thermodynamic and kinetic assessments, the precipitation mechanisms of the hybrid reinforcements were discussed, and the formation of both TiB_w and TiB_2p from the local melting zone was thermodynamically favored. The precipitation kinetics were mainly controlled by a solid-state diffusion of B atoms. By forming a compact compound layer, in situ reactions were divided into two stages, where Zener growth and Dybkov growth prevailed, respectively. Accordingly, the competitive precipitation behavior was attributed to the transition of the growth model during the reaction process.